Characterization of the mechanical behavior of intrapulmonary percussive ventilation

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Geplaatst door: Han Franssen op 2015-12-21 13:23:37

E Fornasa1, M Ajčević and A Accardo Physiological Measurement Volume 34 Number 12 E Fornasa et al 2013 Physiol. Meas. 34 1583 doi:10.1088/0967-3334/34/12/1583 A new device delivering intrapulmonary percussive ventilation (IPV), called Impulsator® (Percussionaire Corporation, Sandpoint, ID, USA), has recently been introduced in an effort to provide effective clearance and to promote homogeneity of ventilation in the lungs of patients with cystic fibrosis. In order to optimize the treatment based on its use, a better understanding of its functioning is still necessary. In fact, up to now, a complete characterization of this device has not been carried out, thus reducing its effective utilization in clinical practice. With the aim of overcoming this lack, in this study, data concerning flow and pressure delivered during in vitro IPV were acquired under different combinations of device settings and respiratory loads. Quantitative information was obtained about the physical variables administered by the device like percussive frequency, ratio of inspiratory to expiratory time, flow and pressure magnitudes and volume exchanged. The analysis of the data determined the relations among these variables and between them and the mechanical loads, laying the basis for an optimal clinical application of the device. Nederlands: Doelstelling: vaststellen van mechanische werking van intrapulmonale percussie ventilatie Setting: in vitro studie Methode: flow en druk gemeten tijdens IPV werden getest met verschillende combinaties van apparaat instellingen en respiratoire volumes. Kwantitatieve informatie verkreeg men via de fysieke variabele zoals; frequentie, ratio inspiratoire/expiratoire tijd, flow en druk en volume veranderingengende. Resultaten: de analyse bepaalde de relaties tussen de variabelen, zowel als tussen de variabelen en de mechanische lading. Hiermee werd een basis gelegd voor een optimale klinische toepassing van de apparatuur.