Safety and effect of intermittent intrapulmonary percussive ventilation on oxygen saturation and hemodynamic functions

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Geplaatst door: Han Franssen op 2016-01-30 10:47:50

Intrapulmonary percussive ventilation (IPV) is a ventilatory technique which is used to clear endobronchial secretions in patients. IPV uses a Phasitron, which delivers rapid, high-flow, minibursts of air mixed with oxygen to the patients. We investigated the safety of IPV on hemodynamic values and the effect of IPV on oxygen saturation and respiratory rate.
From April until August 2011 we investigated 42 consecutive patients admitted to our eight-bed adult general ICU with respiratory failure. Variables such as heart rate, mean arterial pressure, respiratory rate, and oxygen saturation were measured and compared at three different time points: before starting IPV therapy, directly after and 15 minutes later. All patients received IPV using a Bird Intrapulmonary Percussionator Ventilator Model IPV-2C for a period of 20 minutes consisting of two cycles of 10 minutes. After the first 10 minutes of IPV therapy in combination with chest compressions the frequency rate was reduced in order to suction the mobilized secretions. This cycle was then repeated. Statistical analysis was done with SPSS version 17. Student's t test was used to compare values before therapy with directly after and after 15 minutes of therapy. P <0.05 was considered significant.
Neither heart rate, mean arterial pressure nor respiratory rate showed any significant change after IPV. Oxygen saturation improved immediately after
We demonstrated that IPV is a safe therapy, and oxygen saturation improved after therapy with IPV.


Doel: Om te onderzoeken of IPV veilig is voor de HD en zuurstof saturatie.

Setting: Enkel centra. Volwassen ICU

Methode: IPV werd toegepast voor twintig minuten bij tweeenveertig patienten met respiratoire falen, wel of niet beademd. HF, MAP, ademhalings frequentie en SpO2 waren geregistreerd op drie meet momenten. Voor, direct na en vijftien minuten na behandeling.

Resultaten: HF, MAP en ademhalings frequentie bleven onveranderd. SpO2 liet significante verbetering zien.

Conclusie: IPV is een veilig therapie voor de HD en verbeterd de SpO2.